
Season 2
The season continued to focus on the surgical residency of five young interns as they try to balance to the challenges of their competitive careers, with the difficulties that determine their personal lives. It was set in the fictional Seattle Grace Hospital, located in the city of Seattle, Washington. Whereas the first season put the emphasis mainly on the unexpected impact the surgical field has on the main characters, the second one provides a detailed perspective on the personal background of each character, focusing on the consequences that their decisions have on their careers. Throughout the season, new story lines were introduced, including the love triangle between Meredith Grey, Derek Shepherd, and Addison Montgomery, the main arc of the season. Also heavily developed was the story line involving Izzie Stevens' relationship with patient Denny Duquette, which resulted in critical acclaim and positive fan response.
Sep 25, 2005 · 27 episodesEpisodes
E1Raindrops Keep Falling on My HeadPicks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is pimped out to relay the hospital gossip back to We
Sep 25, 2005 · 43 min
E2Enough Is EnoughThere's tension between Meredith and Addison. We find out why Derek and Addison aren't together. Bailey puts George on an impossible case. The rest of
Oct 2, 2005 · 43 min
E3Make Me Lose ControlCristina and Meredith try to figure out if Cristina should tell Burke that she's pregnant right before Cristina faces an emergency. Alex and Izzie get
Oct 9, 2005 · 43 min
E4Deny, Deny, DenyAs Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor any. And Meredith's
Oct 16, 2005 · 43 min
E5Bring the PainCristina goes right back to working right after being discharged. Izzie isn't talking to Alex. Derek and Meredith treat a patient. George and Alex get
Oct 23, 2005 · 43 min
E6Into You Like a TrainTrain Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work wi
Oct 30, 2005 · 43 min
E7Something to Talk AboutCristina, Izzie and Meredith take care of Shane, a man who appears to be crazy and claims that he is pregnant. Shane's case induces a spreading fascin
Nov 6, 2005 · 43 min
E8Let It BeMeredith tries to avoid the Shepherds. Cristina and Burke go out on a date and end up getting caught up in their jobs. Derek asks Meredith not to igno
Nov 13, 2005 · 43 min
E9Thanks for the MemoriesIt's Thanksgiving at Seattle Grace Hospital but the holiday's festivites are less than in order. Meredith and Derek try to counsel a family after thei
Nov 20, 2005 · 43 min
E10Much Too MuchDorie Russell is waiting for quintuplets, all 5 girls. Her husband seems more concerned than she is but she is set to bring her babies to their term o
Nov 27, 2005 · 43 min
E11Owner of a Lonely HeartCristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get
Dec 4, 2005 · 43 min
E12Grandma Got Run Over By a ReindeerThe holiday season has started but not everyone is in a festive mood. This is Alex's last day in the hospital unless he passes his boards practical ex
Dec 11, 2005 · 43 min
E13Begin the BeginCristina is bothered by a new year's mandatory work limit. Izzie patient, Denny Duquette, wants two things: 1. a heart transplant, 2. Izzie. Addison d
Jan 15, 2006 · 43 min
E14Tell Me Sweet Little LiesMeredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. George is given a hard task t
Jan 22, 2006 · 43 min
E15Break on ThroughAll the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves. George refuses to cross the picket line and finally
Jan 29, 2006 · 43 min
E16It's the End of the WorldAn explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" f
Feb 5, 2006 · 43 min
E17As We Know ItDerek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dea
Feb 12, 2006 · 43 min
E18YesterdayDerek and Addison's relationship is rocked to the core when a former friend comes to Seattle Grace and his presence promises to shake things up for a
Feb 19, 2006 · 43 min
E19What Have I Done to Deserve This?Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what's up. Derek and Addi
Feb 26, 2006 · 43 min
E20Band-Aid Covers the Bullet HoleThe doctors are up to their necks in their usual levels of drama. Meredith is dealing with the backlash of sleeping with George, George and Burke are
Mar 12, 2006 · 43 min
E21SuperstitionAfter a series of deaths at the hospital some of the staff become very superstitious. Izzie worries about Denny and gets confronted by Alex. A patien
Mar 19, 2006 · 43 min
E22The Name of the GameMeredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew's surgery bec
Apr 2, 2006 · 43 min
E23Blues for Sister SomeoneAddison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient's husband won't use contraceptives. Derek tre
Apr 30, 2006 · 43 min
E24Damage CaseThe staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that
May 7, 2006 · 43 min
E2517 SecondsGeorge and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and h
May 14, 2006 · 43 min
E26Deterioration of the Fight or Flight ResponseDenny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on Burke who
May 15, 2006 · 43 min
E27Losing My ReligionThis episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie
May 15, 2006 · 43 min